PARP Inhibitors in Prostate Cancer: Practical Application of Recent Advances to Ensure Equitable Care in Rural and Underserved Populations

Release Date June 28, 2024
Expiration Date June 28, 2025
Format Webcast
CME 1.0 credit
CE 1.0 contact hours
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Acknowledgement

This activity is provided by Talem Health and RME Collaborative.

This online program is recorded content from the live session at Oncology Congress Spring 2024 and is co-supported by independent medical education grants from Astellas; AstraZeneca Pharmaceuticals; Bristol Myers Squibb; Daiichi Sankyo, Inc.; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. This activity is supported by independent medical education grants from AstraZeneca Pharmaceuticals; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc.

Credit Available

  • Physicians — maximum of 1.0 AMA PRA Category 1 Credit
  • Nurses — 1.0 Contact Hour (0.75 contact hour of pharmacotherapy credit)
  • Pharmacists — 1.0 Contact Hour (0.1 CEUs)

All other healthcare professionals completing this course will be issued a statement of participation.

Target Audience

This activity is designed specifically for oncologists, advanced practice providers, and other members of the healthcare team who serve patients from rural and underserved communities.

Program Overview

In the United States, prostate cancer is the second-leading cause of cancer-related mortality among men. While most prostate cancers are detected early, more than 5% of patients have metastatic disease, and over 30% develop disease recurrence. Additionally, a considerable portion of these patients develop metastatic castration-resistant prostate cancer (mCRPC), which has a poor prognosis. In this activity, expert faculty will review the latest advances in treatment and genomic sequencing for prostate cancer, including use of PARP inhibitors, as well as new and emerging therapies in the pipeline. Strategies to improve risk stratification and overcome barriers to cancer care in rural and underserved communities will also be discussed.

This enduring activity is a recorded session from Oncology Congress that took place on April 13, 2024.

Learning Objectives

Upon completion of this activity, participants should be better able to:  

  • Describe the mechanism of action and clinical rationale for using PARP inhibitors in the management of mCRPC
  • Evaluate recent clinical trial data for novel and emerging PARP inhibitor therapy for mCRPC
  • Integrate the latest data and expert guidance on PARP inhibitor therapy to develop personalized treatment plans for patients with mCRPC
  • Employ interprofessional strategies to overcome barriers and support equitable prostate cancer care for rural and underserved populations

Faculty

Neeraj Agarwal, MD, FASCO
Professor of Medicine
Senior Director of Clinical Research
Director, Genitourinary Oncology Program
NCICCC Huntsman Cancer Institute, University of Utah
Salt Lake City, UT

Chris Prakash, MD
Director, Quality Services - Texas Oncology
Chair, Medical Oncology Quality - Texas Oncology
President, Texas Society of Clinical Oncology
Medical Director, Texas Oncology - Paris
Paris, TX

Joint Accreditation Statement

In support of improving patient care, Talem Health is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation Statement

Physician Continuing Medical Education
Talem Health designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education
The maximum number of hours awarded for this Continuing Nursing Education activity is 1.0 contact hour. Designated for 0.75 contact hour of pharmacotherapy credit for Advanced Practice Registered Nurses.

Continuing Pharmacy Education
Talem Health designates this continuing education activity for 1.0 contact hour(s) (0.1 CEUs) of the Accreditation Council for Pharmacy Education.
(Universal Activity Number – JA4008332-0000-24-044-H01-P)
Type of Activity: Application

Disclosure of Conflicts of Interest

Talem Health adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All identified conflicts of interest are thoroughly vetted and mitigated according to Talem Health policy. Talem Health is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

All relevant financial relationships have been mitigated. 

The faculty reported the following relevant financial relationships with ineligible entities related to the educational content of this CE activity:

Faculty

Neeraj Agarwal, MD, FASCO, has disclosed the following relevant financial relationships: contracted research (awarded to institution) for Arvinas, Inc., Astellas Pharma, Inc., AstraZeneca Pharmaceuticals, Bayer Corporation, Bristol Myers Squibb, Calithera Biosciences, Celldex Therapeutics, Inc., CRISPR Therapeutics, Eisai Co., Ltd., Eli Lilly and Company, EMD Serono, Inc., Exelixis, Inc., Genentech, Inc., Gilead Sciences, Inc., GSK, Immunomedics, Inc. (now Gilead Sciences, Inc.), Janssen Pharmaceuticals, LAVA Therapeutics, Merck & Co., Inc., Nektar Therapeutics, Neoleukin Therapeutics, Inc., Novartis Pharmaceuticals, ORIC Pharmaceuticals, Pfizer, Inc., Roche, Sanofi, Seattle Genetics, and TRACON Pharmaceuticals, Inc.

Chris Prakash, MD, has disclosed the following relevant financial relationships: speakers’ bureau/honoraria from Myriad Genetics, Inc.

Planners, Managers, and Reviewer 

The Talem Health planners, managers, and reviewer have nothing to disclose.

Instructions for Participation and Credit

This activity is offered at no cost to participants. To receive CME credit, participants must:

  1. Read the CME/CE information, including learning objectives and disclosure statements.
  2. Complete the pre-test.
  3. View the online activity.
  4. Complete the post-test and evaluation form.

A post-test score of 67% or higher is required to obtain credit. Your certificate will be made available for immediate download.

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

©RME Collaborative, a division of Talem Health, LLC. All Rights Reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Talem Health, LLC is prohibited.

Media

Internet activity

Fee Information

There is no fee for this educational activity.

Contact Information

General Questions
For questions about this activity, please contact RME Collaborative (a division of Talem Health) at 800-913-9370 or cme@cmeruralhealth.com.